Poppers

Poppers is a slang term for various alkyl nitrites inhaled for recreational purposes, particularly amyl nitrite, butyl nitrite, isopropyl nitrite and isobutyl nitrite. Amyl nitrite is used medically as an antidote to cyanide poisoning, but the term "poppers" refers specifically to recreational use. Amyl nitrite and several other alkyl nitrites, which are present in products such as air freshener and video head cleaner, are often inhaled with the goal of enhancing sexual pleasure. These products have also been part of the club culture from the 1970s disco scene to the 1980s and 1990s rave scene. Poppers have a long history of abuse due to the rush of warm sensations and dizziness experienced when the vapours are inhaled. Poppers are used recreationally by substance abusers. Poppers have a low risk of harm to society and the individual compared to other recreational drugs; however, serious adverse effects can occur following acute exposure, and with heavy long-term use there is a potential for neurological damage. Swallowing or aspirating the liquid, rather than inhaling the vapours, is particularly dangerous and can prove fatal. Direct, concentrated inhalation of amyl nitrite and the other light alkyl nitrites leads to a non-specific relaxation of smooth muscle, resulting in coronary vasodilation and decreased systemic vascular resistance and left ventricular preload and afterload. In addition, the use of poppers has been associated with an increased risk of HIV infection and AIDS, though research concluded the relationship was not causal and due to the correlation with high-risk sexual behavior.

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