Oxilorphan

Oxilorphan is an opioid antagonist from the morphinan family of drugs. Oxilorphan is a non-selective opioid which is a antagonist but a partial agonist. It has similar effects to naloxone, and around the same potency as an antagonist. Oxilorphan has some weak partial agonist effects and can produce hallucinogenic effects at high doses, suggesting some kappa opioid agonist action. It was trialled for the treatment of opiate addiction, but was not developed commercially.

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